Three children have been taken to hospital with serious but not life-threatening injuries and another 13 were treated at the scene of the crash involving a school bus in Wellhouse Lane, according to Hampshire Police.
A double-decker bus has collided with a bridge in Winchester.
The top of the bus has been severely damaged in the crash with a railway bridge, according to ITV.
Police, fire and ambulance have all been sent to the scene.
A police spokesman said: “We are dealing with a serious collision on Well House Lane, Winchester, after a school bus collided with a railway bridge.
“There are no life-threatening injuries. A road closure is in place on Well House Lane from Andover Road North to School Lane. Thank you for your patience.”
A spokesperson for Hampshire Fire and Rescue Service said: “Crews from Winchester, Eastleigh, Andover, Redbridge and Basingstoke were mobilised at 8.12am this morning to Well House Lane in Winchester.”
A Hampshire Police spokesman added that the three pupils taken to hospital suffered serious but not life-threatening injuries.
He said: “We were called at 8.10am today, 10 September, to reports of a serious collision on Wellhouse Lane, Winchester, after a school bus collided with a railway bridge causing significant damage to the top of the bus.
“Three students with serious, but not life-threatening injuries, have been taken to hospital.
“A further 13 students with minor injuries have been dealt with at the scene.
“All the students involved are aged between 11 and 16.
“A road closure is in place on Well House Lane from the junction with Andover Road North to School Lane to enable us to deal with this incident. We thank you for your patience.
“We are working in cooperation with the school and Hampshire County Council children’s services to provide support to the students and their parents.”